Adrenocortical suppression in workers employed in manufacturing synthetic glucocorticosteroids: solutions to a problem.
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Adrenocortical suppression in workers employed in manufacturing synthetic glucocorticosteroids: solutions to a problem.
Earlier studies showed gross adrenocortical suppression in three workers employed in manufacturing synthetic glucocorticoids. A further nine had either recognisable abnormalities of their responses to tetracosactrin or evidence of chronic skin contact with glucocorticoids. By 1978 the mean morning cortisol concentration of 20 workers employed in active steroid processes was 235 nmol/1 +/- 28.6 ...
متن کاملAdrenocortical suppression in workers manufacturing synthetic glucocorticoids.
A man who had worked for 16 years in the manufacture of a potent corticosteroid was found to be suffering from chronic adrenocortical insufficiency attributed to chronic absorption of the glucocorticoid. Eleven other symptom-free workers were therefore screened. Two of these workers, like the first patient, gave grossly abnormal responses to the Synacthen (tetracosactrin) test; one had been emp...
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ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 1982
ISSN: 1351-0711
DOI: 10.1136/oem.39.2.179